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Mitral Valve Regurgitation - Symptoms, Diagnosis and Treatment

What Is Mitral Valve Regurgitation ?

Mitral Valve Regurgitation, also known as mitral insufficiency or a leaky mitral valve, occurs when the mitral valve fails to seal completely, allowing blood to flow backward from the left ventricle into the left atrium Cleveland Clinic. This backward flow forces the heart to work harder, and over time may progress from a mild, often symptomless condition to a serious cardiac issue Cleveland Clinic

"Early detection and minimally invasive repair offer the best outcomes in mitral valve regurgitation."

Symptoms of Mitral Valve Regurgitation

“Breathlessness, fatigue, or palpitations can be early signs of mitral valve regurgitation. Don’t ignore them—early diagnosis prevents serious heart complications.” — Dr. Vishal Khante

A cardiologist typically begins diagnosis with a comprehensive physical examination and discussion of your symptoms and medical history Mayo Clinic. A whooshing heart murmur may be detected using a stethoscope Mayo Clinic.

  • Common tests include:

    • Echocardiogram (TTE or TEE) to assess valve structure and regurgitation severity Mayo Clinic

    • Electrocardiogram (ECG) to detect arrhythmias like atrial fibrillation Mayo Clinic

    • Chest X-ray to check for enlarged heart or fluid accumulation in the lungs Mayo Clinic

    • Stress/exercise testing to observe symptoms under exertion Mayo Clinic

    • Cardiac catheterization, primarily if other diagnostics are inconclusive Mayo Clinic

Diagnosis & Testing

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1. Medical Management & Monitoring

For mild MR, lifestyle adjustments (healthy diet, regular monitoring, and medications) might suffice Mayo Clinic+1University Hospitals. Medications may include:

  • Diuretics to reduce fluid overload Mayo Clinic

  • Anticoagulants to prevent blood clots in cases with atrial fibrillation Mayo Clinic

  • Vasodilators (e.g., ACE inhibitors, hydralazine) to reduce heart workload in chronic MR Wikipedia+1

2. Minimally Invasive and Interventional Options

  • MitraClip is a catheter-based procedure that clips mitral valve leaflets together—ideal for patients not suitable for open-heart surgery WikipediaVerywell Health.

  • In some instances, doctors may deploy clips or plugs via catheter approaches, offering a less invasive alternative to surgery Mayo Clinic.

3. Surgical Intervention

When MR is severe or symptomatic:

  • Mitral Valve Repair is preferred whenever feasible—procedures include annuloplasty (valve ring reinforcement), leaflet resection, or artificial chordae implantation Wikipedia+1. Repair offers better outcomes and often avoids long-term anticoagulation Wikipedia.

  • Mitral Valve Replacement may be necessary when repair isn’t viable, using mechanical or tissue valves WikipediaAmerican Hospital.

  • Minimally invasive surgical techniques (keyhole or port-access) reduce incisions and speed recovery WikipediaMayo Clinic.

Treatment Strategy